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Cat. No.: HY-16974S

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Afoxolaner-d₆

Afoxolaner-d₆ is the deuterium labeled Afoxolaner (HY-16974). Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.

For research use only. We do not sell to patients.

Formula: C₂₆H₁₁D₆ClF₉N₃O₃
Molecular Weight:631.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Afoxolaner-d₆ Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
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Bioz

Biological Activity

Description

All Parasite Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 1093861-60-9
Molecular Weight 631.91
Formula C₂₆H₁₁D₆ClF₉N₃O₃
SMILES

O=C(NCC(NCC(F)(F)F)=O)C1=C2C([2H])=C([2H])C([2H])=C([2H])C2=C(C3=NOC(C(F)(F)F)(C4=CC(C(F)(F)F)=CC(Cl)=C4)C3)C([2H])=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.