Antitumor agent-63
Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition.
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- CAS No.: 1627600-90-1
- Formule: C38H46N4O18
- Masse moléculaire:846.79
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Top1 |
Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1627600-90-1
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Masse moléculaire 846.79
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Formule C38H46N4O18
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SMILES
O[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)OC(N)=O)[C@H]1O[C@@H]([C@H]([C@@H]([C@@H](O2)CO)O)O)[C@H]2OCCOCCNC(O[C@]3(C4=C(COC3=O)C(N5C(C6=NC7=CC=CC=C7C=C6C5)=C4)=O)CC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antitumor agent-63 Related Classifications
HY-146094 Related Classifications
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