hDHODH-IN-7
DHODH-IN-9 (Compound 10k) is an azine-bearing analogue and is a human dihydroorotate dehydrogenase inhibitor. DHODH-IN-9 has antiviral effect with a pMIC50 of 7.4.
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- CAS No.: 1644156-41-1
- Formule: C21H23FN4O
- Masse moléculaire:366.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
pMIC50: 7.4 (DHODH)[1]
DHODH-IN-9 (Compound 10k) is a corresponding pyridazine homologue from 3-chloro-6-cyclopropylpyridazine. With few variations, the pattern of antiviral effect for analogues featuring a 5-cyclopylpyridine is somehow mirroring the one seen for the 5-ethylpyrimidyl bearing homologues. DHODH-IN-9 (Compound 10k) is a good antiviral of this group of analogue[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1644156-41-1
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Masse moléculaire 366.43
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Formule C21H23FN4O
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SMILES
CC(C)OC1=NN(C2=NC=C(C3CC3)C=N2)C(C)=C1CC4=CC=CC=C4F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)