1. Metabolic Enzyme/Protease
    Cell Cycle/DNA Damage
    Anti-infection
  2. Dihydroorotate Dehydrogenase
    DNA/RNA Synthesis
    Influenza Virus
  3. hDHODH-IN-4

hDHODH-IN-4 

Cat. No.: HY-128787 Purity: 99.75%
Handling Instructions

hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8.

For research use only. We do not sell to patients.

hDHODH-IN-4 Chemical Structure

hDHODH-IN-4 Chemical Structure

CAS No. : 1644156-56-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 435 In-stock
Estimated Time of Arrival: December 31
5 mg USD 395 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8[1].

Molecular Weight

364.44

Formula

C₂₁H₂₄N₄O₂

CAS No.

1644156-56-8

SMILES

OC(C1=CC=CC=C1)C2=C(C)N(C3=NC=C(C4CC4)C=N3)N=C2OC(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (342.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7439 mL 13.7197 mL 27.4394 mL
5 mM 0.5488 mL 2.7439 mL 5.4879 mL
10 mM 0.2744 mL 1.3720 mL 2.7439 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: 6.25 mg/mL (17.15 mM); Clear solution; Need ultrasonic

*All of the co-solvents are provided by MCE.
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

hDHODH-IN-4Dihydroorotate DehydrogenaseDNA/RNA SynthesisInfluenza VirusDHODHantiviral,infectiousdiseasesvirusreplicationInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
hDHODH-IN-4
Cat. No.:
HY-128787
Quantity:
MCE Japan Authorized Agent: