1644156-56-8
1644156-56-8
Chemical Structure
hDHODH-IN-4
- CAS No.: 1644156-56-8
- Formula:C21H24N4O2
- Molecular Weight:364.44
IUPAC Name: (1-(5-cyclopropylpyrimidin-2-yl)-3-isopropoxy-5-methyl-1H-pyrazol-4-yl)(phenyl)methanol
InChIKey: BSNKBAPMWCMENP-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC=C1)C2=C(C)N(C3=NC=C(C4CC4)C=N3)N=C2OC(C)C
Biological Activity: hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8[1].
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hDHODH-IN-4 | 99.73% | hDHODH-IN-4 is a potent human dihydroorotate dehydrogenase (DHODH) inhibitor, with a pIC50 of 7.8 for human recombinant DHODH. hDHODH-IN-4 inhibits measles virus replication, with a pMIC50 of 8.8. | ||||||||||||||||||||
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References
Keywords
