1. GPCR/G Protein
  2. Glucocorticoid Receptor
  3. Dexamethasone palmitate

Dexamethasone palmitate (Synonyms: DXP)

Cat. No.: HY-128922 Purity: >98.0%
Handling Instructions

Dexamethasone palmitate (DXP) is a prodrug of Dexamethasone, which is a glucocorticoid receptor agonist. Dexamethasone palmitate (DXP) has a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Anti-inflammatory agent.

For research use only. We do not sell to patients.

Dexamethasone palmitate Chemical Structure

Dexamethasone palmitate Chemical Structure

CAS No. : 14899-36-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 69 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 80 In-stock
Estimated Time of Arrival: December 31
50 mg USD 170 In-stock
Estimated Time of Arrival: December 31
100 mg USD 290 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Dexamethasone palmitate (DXP) is a prodrug of Dexamethasone, which is a glucocorticoid receptor agonist[1]. Dexamethasone palmitate (DXP) has a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone[2]. Anti-inflammatory agent.

Molecular Weight

630.87

Formula

C₃₈H₅₉FO₆

CAS No.

14899-36-6

SMILES

C[[email protected]@]12[[email protected]](C[[email protected]@H](C)[[email protected]]2(O)C(COC(CCCCCCCCCCCCCCC)=O)=O)([H])[[email protected]@]3([H])[[email protected]@](F)([[email protected]@]4(C(CC3)=CC(C=C4)=O)C)[[email protected]@H](O)C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (396.28 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5851 mL 7.9256 mL 15.8511 mL
5 mM 0.3170 mL 1.5851 mL 3.1702 mL
10 mM 0.1585 mL 0.7926 mL 1.5851 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (3.30 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.30 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Dexamethasone palmitate
Cat. No.:
HY-128922
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