2. Cell Cycle/DNA Damage Apoptosis
  3. DNA/RNA Synthesis Apoptosis MDM-2/p53
  4. Dibenz[a,h]anthracene

Dibenz[a,h]anthracene  (Synonyms: DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene)

Cat. No.: HY-W013053
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Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms.

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Dibenz[a,h]anthracene Chemical Structure

Dibenz[a,h]anthracene Chemical Structure

CAS No. : 53-70-3

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Other Forms of Dibenz[a,h]anthracene:

Dibenz[a,h]anthracene Related Antibodies

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Description

Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms[1][2].

Molecular Weight

278.35

Formula

C22H14
CAS No.
Appearance

Solid

SMILES

C12=CC=CC=C1C3=CC(C=CC4=CC=CC=C45)=C5C=C3C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Dibenz[a,h]anthracene Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dibenz[a,h]anthracene53-70-3DBA 1,2,5,6-Dibenzanthracene Benzo[k]tetrapheneDNA/RNA SynthesisApoptosisMDM-2/p53polycyclic aromatic hydrocarbonPAHDNA adductcell cycle arrestTp53Inhibitorinhibitorinhibit

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