53-70-3
![Dibenz[a,h]anthracene Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-w013053.gif "Dibenz[a,h]anthracene Chemical Structure")
53-70-3
Chemical Structure
Dibenz[a,h]anthracene
Synonym(s): DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene
- CAS 番号: 53-70-3
- Formula:C22H14
- Molecular Weight:278.35
IUPAC Name: benzo[k]tetraphene
InChIKey: LHRCREOYAASXPZ-UHFFFAOYSA-N
SMILES: C12=CC=CC=C1C3=CC(C=CC4=CC=CC=C45)=C5C=C3C=C2
Biological Activity: Dibenz[a,h]anthracene (DBA) is an orally active polycyclic aromatic hydrocarbon, a by-product of incomplete combustion of organic matter, a potent carcinogen, and an agonist of AhR. Dibenz[a,h]anthracene induces dose-dependent increases in DNA adduct formation and lacZ mutation frequency. Dibenz[a,h]anthracene upregulates St3gal5. Dibenz[a,h]anthracene can be used in cancer-related research[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dibenz[a,h]anthracene | 98.0% | Dibenz[a,h]anthracene (DBA) is an orally active polycyclic aromatic hydrocarbon, a by-product of incomplete combustion of organic matter, a potent carcinogen, and an agonist of AhR. Dibenz[a,h]anthracene induces dose-dependent increases in DNA adduct formation and lacZ mutation frequency. Dibenz[a,h]anthracene upregulates St3gal5. Dibenz[a,h]anthracene can be used in cancer-related research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dibenz[a,h]anthracene (Standard) | ≥98% | Dibenz[a,h]anthracene (Standard) is the analytical standard of Dibenz[a,h]anthracene. This product is intended for research and analytical applications. Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dibenz[a,h]anthracene-d14 | Dibenz[a,h]anthracene-d14 is the deuterium Dibenz[a,h]anthracene. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzo[a]pyrene | 99.98% | Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Chrysene (Standard) | ≥98% | Chrysene (Standard) is the analytical standard of Chrysene. This product is intended for research and analytical applications. Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH) known for its recalcitrance and carcinogenic properties. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dibenzo(a,i)pyrene | 98.0% | Dibenzo (a,i) pyrene is a polycyclic aromatic hydrocarbon and also a carcinogenic ligand of the TCDD (Ah) receptor. Dibenzo (a,i) pyrene binds to the TCDD (Ah) receptor in rat liver. Dibenzo (a,i) pyrene induces DNA adduct formation and upregulates the protein levels of p53 and p21WAF1 in diploid lung fibroblasts. Dibenzo (a,i) pyrene alters the cell cycle distribution of diploid lung fibroblasts, increasing the proportion of cells in the S phase, decreasing the proportions of cells in the G0/G1 and G2/M phases, and causing S phase delay/arrest. Dibenzo (a,i) pyrene is applicable for cancer research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Phenanthrene | 99.82% | Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzo[f]tetraphene | Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benzo[c]phenanthrene | Benzo[c]phenanthrene has carcinogenic activity. Benzo[c]phenanthrene can be used as a substrate or intermediate. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Benz[a]anthracene | 99.90% | Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Picene | Picene is a polycyclic aromatic hydrocarbon of environmental relevance. Picene can be widely distributed in the environment as the result of incomplete combustion of organic matter. Picene is found to be inactive as complete carcinogen, while it acts in a high dose as a weak tumor initiator. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Phenanthrene-13C6 | 99.9% | Phenanthrene-13C6 is the 13C labeled Phenanthrene (HY-B1727). Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Phenanthrene-13C2 | Phenanthrene-13C2 is the 13C-labeled Phenanthrene (HY-B1727). Phenanthrene is an orally active polycyclic aromatic hydrocarbon (PAH) that induces inflammation, oxidative stress, and apoptosis. Additionally, phenanthrene is commonly used to detect or assess PAH pollution in the environment. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
