MAPK ligand 1
MAPK ligand 1 is an apoptosis inducer and Bcl-xL/MAPK ligand that can be used to synthesize the Bcl-xL-targeted PROTAC degrader (HY-176740). MAPK ligand 1 triggers apoptosis through the mitochondrial pathway, MAPK pathway, reduction of mitochondrial membrane potential and elevation of reactive oxygen species levels. MAPK ligand 1 inhibits colony formation and migration of cancer cells, as well as angiogenesis of endothelial cells. MAPK ligand 1 can be used in the research of hepatocellular carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 2566503-77-1
- Formula: C20H13NO3
- Molecular Weight:315.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Bcl-xL |
Chemical Information
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CAS No. 2566503-77-1
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Molecular Weight 315.32
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Formula C20H13NO3
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SMILES
OC(C1=CC2=C(NC(C3=CC=CC4=C3C=CC=C4)=CC2=O)C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAPK ligand 1 Related Classifications
HY-176741 Related Classifications
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