VU0364739
Based on 1 Customer Validation
VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation.
For research use only. We do not sell to patients.
- Purity: 99.16%
- CAS No.: 1244639-78-8
- Formula: C26H27FN4O2
- Molecular Weight:446.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Phospholipase Isoforms
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Biological Activity
PLD[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
20 nM
Compound: 22a
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Inhibition of human GST-tagged PLD2A in human HEK293 cells
Inhibition of human GST-tagged PLD2A in human HEK293 cells
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[PMID: 20735042] |
Chemical Information
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CAS No. 1244639-78-8
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Appearance Solid
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Molecular Weight 446.52
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Formula C26H27FN4O2
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Color Off-white to light yellow
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SMILES
O=C(C1=CC2=C(C=CC=C2)C=C1)NCCN3CCC4(CC3)C(NCN4C5=CC(F)=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (447.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2395 mL | 11.1977 mL | 22.3954 mL | 55.9885 mL |
| 5 mM | 0.4479 mL | 2.2395 mL | 4.4791 mL | 11.1977 mL | |
| 10 mM | 0.2240 mL | 1.1198 mL | 2.2395 mL | 5.5989 mL | |
| 15 mM | 0.1493 mL | 0.7465 mL | 1.4930 mL | 3.7326 mL | |
| 20 mM | 0.1120 mL | 0.5599 mL | 1.1198 mL | 2.7994 mL | |
| 25 mM | 0.0896 mL | 0.4479 mL | 0.8958 mL | 2.2395 mL | |
| 30 mM | 0.0747 mL | 0.3733 mL | 0.7465 mL | 1.8663 mL | |
| 40 mM | 0.0560 mL | 0.2799 mL | 0.5599 mL | 1.3997 mL | |
| 50 mM | 0.0448 mL | 0.2240 mL | 0.4479 mL | 1.1198 mL | |
| 60 mM | 0.0373 mL | 0.1866 mL | 0.3733 mL | 0.9331 mL | |
| 80 mM | 0.0280 mL | 0.1400 mL | 0.2799 mL | 0.6999 mL | |
| 100 mM | 0.0224 mL | 0.1120 mL | 0.2240 mL | 0.5599 mL |
VU0364739 Related Classifications
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