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Medroxyprogesterone acetate

(Synonyms: Medroxyprogesterone 17-acetate; Farlutin)
35 Cited Publications
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Based on 35 publication(s) in Google Scholar

Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.

For research use only. We do not sell to patients.

  • Purity: 99.88%
  • CAS No.: 71-58-9
  • Formula: C24H34O4
  • Molecular Weight:386.52
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Medroxyprogesterone acetate Chemical Structure
    Medroxyprogesterone acetate Chemical Structure
  • Experimental Validation Results for Medroxyprogesterone acetate
  • Experimental Validation Results for Medroxyprogesterone acetate
  • Experimental Validation Results for Medroxyprogesterone acetate
  • Experimental Validation Results for Medroxyprogesterone acetate
  • Experimental Validation Results for Medroxyprogesterone acetate
  • Experimental Validation Results for Medroxyprogesterone acetate
CAS No.: 71-58-9
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Medroxyprogesterone acetate Chemical Structure
    Medroxyprogesterone acetate Chemical Structure
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    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: EMBO J. 2024 Nov;43(21):5018-5036. [Abstract]

    Customer Validation
     Human ESC cell line (hESCs) was treated with 8-bromo-cAMP (0.5 mM) plus Medroxyprogesterone acetate (MPA, 1 μM) for different times, and westernblotting assay was used to detect the expression of CDKN2A, CDKN1A, TP53 (indicator of cell senescence) and PRL.

  • 1/16

    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: Mol Med. 2024 Sep 12;30(1):147. [Abstract]

    Customer Validation
     The growth of subcutaneously transplanted tumors in mice (n=6). Daily intraperitoneal injections (100 mg/kg MA, Medroxyprogesterone acetate) were administered, and tumor size was measured every 4 days to calculate tumor volume.

  • 1/16

    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: Mol Med. 2024 Sep 12;30(1):147. [Abstract]

    Customer Validation
     TUNEL staining to detect apoptosis of tumor cells in mice in each group (n=6), daily intraperitoneal injections (100 mg/kg MA, Medroxyprogesterone acetate) were administered.

  • 1/16

    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 May 10;8(1):183. [Abstract]

    Customer Validation
     Cisplatin-resistant OVCAR-1 CP were pretreated with three indicated drugs (Farlutin, 10 μM) for 24 h before treatment with cisplatin for another 6 h (Scale bar: 5 μm). The localization of NPM1 was detected by immunofluorescence to indicate the ribosomal stress.

  • 1/16

    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 May 10;8(1):183. [Abstract]

    Customer Validation
     The cells were pretreated with the three indicated drugs for 24 h (Farlutin, 10 μM). Colony-formation assay was used to determine the drug sensitivity to cisplatin.

  • 1/16

    Medroxyprogesterone acetate purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 May 10;8(1):183. [Abstract]

    Customer Validation
     Cell viability assay was performed for cisplatin treated ovarian cancer organoids with/without pretreatment with Farlutin, 10 μM, 120 h.

  • Medroxyprogesterone acetate