L-764406
L-764406 is a non-thiazolidinedione (TZD)-type PPARg nuclear receptor ligand with high affinity. L-764406 has significant binding ability to PPARg (IC50=70 nM). L-764406 exhibited partial agonist activity and induced expression of the adipocyte-specific gene aP2 in chimeric receptors expressing the PPARg LBD and the corresponding reporter gene, as well as in 3T3-L1 cells. In contrast, L-764406 showed no activity in cells transfected with chimeric receptors containing PPARa or PPARd LBDs.
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- No. CAS: 227002-04-2
- Fòrmula: C15H11ClN2O2S
- Peso molecular:318.78
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
PPARg Nuclear Receptor[1]
Chemical Information
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No. CAS 227002-04-2
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Peso molecular 318.78
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Fòrmula C15H11ClN2O2S
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SMILES
O=S(CC1=NC2=CC=CC=C2N=C1Cl)(C3=CC=CC=C3)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-764406 Related Classifications
HY-121579 Related Classifications
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