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Referencia número: HY-103404

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PNU-96415E

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 170856-41-4
Fòrmula: C₂₁H₂₇Cl₂FN₂O
Peso molecular:413.36

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PNU-96415E Chemical Structure

No. CAS: 170856-41-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Actividad biológica

Descripciòn

PNU-96415E is a selective D₄/5-HT_2A antagonist. PNU-96415E may have potential antipsychotic efficacy^[1].

IC₅₀ & Target^[1]

D₄ Receptor

5-HT_2A Receptor

Ver todos los productos específicos de isoformas Dopamine Receptor :

Ver todos los productos específicos de isoformas 5-HT Receptor :

In Vivo

PNU-96415E blockes 5-HTP-induced bead twitches in mice and stereotypic behaviours produced by high doses of amphetamine and methylphenidate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 170856-41-4
Peso molecular 413.36
Fòrmula C₂₁H₂₇Cl₂FN₂O
SMILES

FC1=CC=C(N2CCN(CCC3C4=CC=CC=C4CCO3)CC2)C=C1.[H]Cl.[H]Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kulkarni SK, et al. Dopamine D4 receptors and development of newer antipsychotic drugs. Fundam Clin Pharmacol. 2000;14(6):529-539. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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PNU-96415E

Ver todos los productos específicos de isoformas Dopamine Receptor

Ver todos los productos específicos de isoformas 5-HT Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

PNU-96415E Related Classifications

HY-103404 Related Classifications