16 Results for "

hypoactive

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "hypoactive" in MCE Product Catalog:

6
6 Publications Verification
Referencia número: HY-B0717
No. CAS: 9002-96-4
Synonyms: TPGS; D-α-Tocopherol polyethylene glycol 1000 succinate; Vitamin E-TPGS
Target:  

Drug Derivative

Áreas de investigación:  

Neurological Disease Metabolic Disease

Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E .
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2
2 Cited Publications
Referencia número: HY-A0095
No. CAS: 167933-07-5
Synonyms: BIMT-17; BIMT-17BS
Áreas de investigación:  

Neurological Disease Cancer

Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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2
2 Cited Publications
Referencia número: HY-A0095A
Synonyms: BIMT-17 hydrochloride (propan-2-ol) hydrate; BIMT-17BS hydrochloride (propan-2-ol) hydrate
Target:  

5-HT Receptor

Áreas de investigación:  

Neurological Disease Cancer

Flibanserin (BIMT-17) hydrochloride (propan-2-ol) hydrate is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride (propan-2-ol) hydrate binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride (propan-2-ol) hydrate shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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1
1 Cited Publications
Referencia número: HY-18678A
No. CAS: 1607799-13-2
Synonyms: PT-141 Acetate
Target:  

Melanocortin Receptor

Áreas de investigación:  

Metabolic Disease

Bremelanotide (PT-141) Acetate is a melanocortin receptor agonist. Bremelanotide Acetate can activate MC4R and increases dopamine release. Bremelanotide Acetate induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide Acetate can be used for the research of hypoactive sexual desire disorders .
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1
1 Cited Publications
Referencia número: HY-18678
No. CAS: 189691-06-3
Synonyms: PT-141
Target:  

Melanocortin Receptor

Áreas de investigación:  

Neurological Disease Metabolic Disease

Bremelanotide (PT-141) is a melanocortin receptor agonist. Bremelanotide can activate MC4R and increases dopamine release. Bremelanotide induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide can be used for the research of hypoactive sexual desire disorders .
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Referencia número: HY-17549
No. CAS: 63547-13-7
Synonyms: CRL 40028
Target:  

Adrenergic Receptor

Áreas de investigación:  

Neurological Disease

Adrafinil (CRL 40028) is an orally active vigilance promoting agent. Adrafinil enhances central noradrenergic transmission, improves spontaneous activity, exploratory behavior, discriminative learning ability and response motivation, but impairs visuospatial working memory. Adrafinil antagonizes Prazosin (HY-B0193)-induced hypoactivity and hypothermia, exerts anticonvulsant effects, and induces sustained enhancement of high-frequency electrocortical activity. Adrafinil can be used for research on decreased alertness and specific cognitive deficits .
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Referencia número: HY-107614G
No. CAS: 325465-93-8
Synonyms: 1-Oleoyl-sn-glycero-3-phosphate sodium (GMP); 1-Oleoyl-LPA sodium (GMP)
1-Oleoyl lysophosphatidic acid sodium (GMP) is the GMP-grade form of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). GMP-grade small molecules serve as auxiliary reagents in cell therapy. 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid signaling molecule. 1-Oleoyl lysophosphatidic acid sodium inhibits lysoPLD-catalyzed hydrolysis of lysophosphatidylcholine and FS-3. 1-Oleoyl lysophosphatidic acid sodium activates LPA1 and LPA2, thereby triggering calcium mobilization, NFATc1 translocation, Rho/ROCK activation, Smad2/3 phosphorylation and c-Fos expression. 1-Oleoyl lysophosphatidic acid sodium induces anxiety-like, depression-like and hypoactivity phenotypes, regulates osteoclast cytoskeleton and viability, reduces osteoclast bone resorptive activity, and drives mesenchymal stem cell differentiation into myofibroblast-like cells. 1-Oleoyl lysophosphatidic acid sodium stimulates the secretion of transforming growth factor-β1 and stromal cell-derived factor-1. 1-Oleoyl lysophosphatidic acid sodium is applicable to research related to anxiety, depression and ovarian cancer .
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Referencia número: HY-A0095B
No. CAS: 147359-76-0
Synonyms: BIMT-17 hydrochloride; BIMT-17BS hydrochloride
Áreas de investigación:  

Neurological Disease Cancer

Flibanserin (BIMT-17) hydrochloride is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-P10015
No. CAS: 1124168-43-9
Target:  

Peptides

Áreas de investigación:  

Endocrinology

Orenetide is an innovative peptide drug developed in the study to restore sexual desire and concomitant functions in women with HSDD (Hypoactive desire disorder)
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Referencia número: HY-A0095R
No. CAS: 167933-07-5
Synonyms: BIMT-17 (Standard); BIMT-17BS (Standard)
Áreas de investigación:  

Neurological Disease Cancer

Flibanserin (Standard) is the analytical standard of Flibanserin. This product is intended for research and analytical applications. Flibanserin (BIMT-17; BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-A0095S
No. CAS: 2122830-90-2
Synonyms: BIMT-17-d4; BIMT-17BS-d4
Flibanserin-d4 (BIMT-17-d4; BIMT-17BS-d4) is the d4-labeled Flibanserin (HY-A0095). Flibanserin is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-A0095AS
No. CAS: 2748630-46-6
Synonyms: BIMT-17-d4 hydrochloride; BIMT-17BS-d4 hydrochloride
Flibanserin-d4 (BIMT-17-d4; BIMT-17BS-d4) hydrochloride is the d4-labeled Flibanserin hydrochloride (HY-A0095B). Flibanserin hydrochloride is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin hydrochloride binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin hydrochloride shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-123480
No. CAS: 755040-97-2
Target:  

5-HT Receptor

Áreas de investigación:  

Neurological Disease

EGIS-7625 is an orally active and selective competitive antagonist of 5-HT2B receptor, with a human Ki value of 1 nM. EGIS-7625 shows low affinity for 5-HT2A and 5-HT2C receptors. The pKi values of EGIS-7625 for human 5-HT2B, 5-HT2A and 5-HT2C are 9.0, 6.2 and 7.7, respectively. EGIS-7625 alleviates mCPP-induced hypoactivity .
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Referencia número: HY-A0095S1
No. CAS: 2122830-91-3
Synonyms: BIMT-17-d4-1; BIMT-17BS-d4-1
Flibanserin-d4-1 (BIMT-17-d4-1; BIMT-17BS-d4-1) is the d4-labeled Flibanserin (HY-A0095). Flibanserin is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-A0095C
No. CAS: 1231148-54-1
Synonyms: BIMT-17 salicylate; BIMT-17BS salicylate
Áreas de investigación:  

Neurological Disease Cancer

Flibanserin (BIMT-17) salicylate is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin salicylate binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin salicylate shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research - .
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Referencia número: HY-123480A
No. CAS: 751462-86-9
Target:  

5-HT Receptor

Áreas de investigación:  

Neurological Disease

EGIS-7625 free base is an orally active and selective competitive antagonist of 5-HT2B receptor, with a human Ki value of 1 nM. EGIS-7625 free base shows low affinity for 5-HT2A and 5-HT2C receptors. The pKi values of EGIS-7625 free base for human 5-HT2B, 5-HT2A and 5-HT2C are 9.0, 6.2 and 7.7, respectively. EGIS-7625 free base alleviates mCPP-induced hypoactivity .
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