751462-86-9
751462-86-9
Chemical Structure
EGIS-7625 free base
- CAS No.: 751462-86-9
- Formula:C18H22N4O2
- Molecular Weight:326.39
InChIKey: ZEFXWOMFCPRXJW-UHFFFAOYSA-N
SMILES: NC(C=C1N2CCN(CC2)CC3=CC=CC=C3)=C(C)C=C1[N+]([O-])=O
Biological Activity: EGIS-7625 free base is an orally active and selective competitive antagonist of 5-HT2B receptor, with a human Ki value of 1 nM. EGIS-7625 free base shows low affinity for 5-HT2A and 5-HT2C receptors. The pKi values of EGIS-7625 free base for human 5-HT2B, 5-HT2A and 5-HT2C are 9.0, 6.2 and 7.7, respectively. EGIS-7625 free base alleviates mCPP-induced hypoactivity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGIS-7625 free base | 99.62% | EGIS-7625 free base is an orally active and selective competitive antagonist of 5-HT2B receptor, with a human Ki value of 1 nM. EGIS-7625 free base shows low affinity for 5-HT2A and 5-HT2C receptors. The pKi values of EGIS-7625 free base for human 5-HT2B, 5-HT2A and 5-HT2C are 9.0, 6.2 and 7.7, respectively. EGIS-7625 free base alleviates mCPP-induced hypoactivity. | ||||||||||||||||||||
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References
Keywords
