GPR176 - G protein-coupled receptor 176 Gene

Also Known as HB-954

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11245

About GPR176

Cytogenetic location: 15q14-q15.1 Genomic coordinates (GRCh38): 15:39,799,008-39,920,266 (from NCBI)

This gene has 5 transcripts (splice variants), 200 orthologues and 3 paralogues. Broad expression in brain (RPKM 2.2), testis (RPKM 1.7) and 22 other tissues.

Summary

Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to Hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008]

GPR176 Products (3)

mRNA Protein Name
NM_001271854.2 NP_001258783.1 G-protein coupled receptor 176 isoform 2
NM_001271855.2 NP_001258784.1 G-protein coupled receptor 176 isoform 3
NM_007223.3 NP_009154.1 G-protein coupled receptor 176 isoform 1

GPR176 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (58 - 319)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 515 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 176

  • probable G-protein coupled receptor 176

Related Diseases

Diseases Alias
Narcolepsy
  • Paroxysmal Sleep

  • Gelineau Syndrome

  • Narcoleptic Syndrome

  • Narcolepsy-Cataplexy Syndrome

  • Cataplexy And Narcolepsy

  • Narcolepsy, Without Cataplexy

  • Gelineau'S Syndrome

  • Narcolepsy With Or Without Cataplexy

  • Narcolepsy Nos

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR176 VGNC VGNC:73045
Mus musculus GPR176 MGD MGI:2685858
Canis familiaris GPR176 VGNC VGNC:41418
Rattus norvegicus GPR176 RGD RGD:621718
Felis catus GPR176 VGNC VGNC:80962
Bos taurus GPR176 VGNC VGNC:29572