GPR176 - G protein-coupled receptor 176 Gene

Homo sapiens

Also known as HB-954

Gene ID: 11245 | Gene type: protein coding

About GPR176

Cytogenetic location: 15q14-q15.1 Genomic coordinates (GRCh38): 15:39,799,008-39,920,266 (from NCBI)

This gene has 5 transcripts (splice variants), 200 orthologues and 3 paralogues. Broad expression in brain (RPKM 2.2), testis (RPKM 1.7) and 22 other tissues.

Summary

Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to Hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008]

GPR176 Products(3)

mRNA	Protein	Name
NM_001271854.2	NP_001258783.1	G-protein coupled receptor 176 isoform 2
NM_001271855.2	NP_001258784.1	G-protein coupled receptor 176 isoform 3
NM_007223.3	NP_009154.1	G-protein coupled receptor 176 isoform 1

GPR176 Protein Structure

7tm_1

0
100
200
300
400
515 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 176

probable G-protein coupled receptor 176

Related Diseases

Diseases

Alias

Narcolepsy

Paroxysmal Sleep	Gelineau Syndrome
Narcoleptic Syndrome	Narcolepsy-Cataplexy Syndrome
Cataplexy And Narcolepsy	Narcolepsy, Without Cataplexy
Gelineau'S Syndrome	Narcolepsy With Or Without Cataplexy
Narcolepsy Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05685	GPR176 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	GPR176	VGNC	VGNC:73045
Mus musculus	GPR176	MGD	MGI:2685858
Canis familiaris	GPR176	VGNC	VGNC:41418
Rattus norvegicus	GPR176	RGD	RGD:621718
Felis catus	GPR176	VGNC	VGNC:80962
Bos taurus	GPR176	VGNC	VGNC:29572

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