METTL7B - methyltransferase like 7B Gene

Also Known as ALDI

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 196410

About METTL7B

This gene has 1 transcript (splice variant), 123 orthologues and 4 paralogues. Biased expression in liver (RPKM 58.0), duodenum (RPKM 25.7) and 7 other tissues.

Summary

Enables thiol S-methyltransferase activity. Predicted to be involved in methylation. [provided by Alliance of Genome Resources, Apr 2022]

METTL7B Products (1)

mRNA Protein Name
NM_152637.3 NP_689850.2 thiol S-methyltransferase METTL7B precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables S-adenosylmethionine-dependent methyltransferase activity IMP
IMP: Inferred from mutant phenotype
33649426 GOA
enables thiol S-methyltransferase activity IDA
IDA: Inferred from direct assay
37137720 GOA
enables thiol S-methyltransferase activity IMP
IMP: Inferred from mutant phenotype
33649426 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

METTL7B Protein Structure

Methyltransf_11

Methyltransf_11: Methyltransferase domain (75 - 172)

  • 0
  • 100
  • 200
  • 244 a.a.
Protein Preferred Names Protein Names

thiol S-methyltransferase METTL7B

  • associated with lipid droplets 1

Related Diseases

Diseases Alias
Optic Atrophy 7 With Or Without Auditory Neuropathy

  • Optic Atrophy 7

  • OPA7

  • Autosomal Recessive Optic Atrophy, Opa7 Type

  • Optic Atrophy-7

  • Atrophy, Optic, Type 7, With/Without Auditory Neuropathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08369 METTL7B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus METTL7B VGNC VGNC:31416
Rattus norvegicus METTL7B RGD RGD:1305205
Canis familiaris METTL7B VGNC VGNC:43181
Mus musculus METTL7B MGD MGI:1918914
Macaca mulatta METTL7B VGNC VGNC:74599
Others METTL7B NCBI