Reln - reelin Gene

Also Known as Rl; Reelen; reeler

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24718

Summary

Predicted to enable very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including nervous system development; response to lithium ion; and response to steroid hormone. Located in several cellular components, including axon; dendrite; and perikaryon. Biomarker of hypothyroidism and status epilepticus. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; familial temporal lobe epilepsy 7; and schizophrenia. Orthologous to human RELN (reelin). [provided by Alliance of Genome Resources, Apr 2022]

Reln Products (1)

mRNA Protein Name
NM_080394.3 NP_536319.3 reelin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
11983443 RGD
involved in cerebral cortex development IEP
IEP: Inferred from expression pattern
10436054 RGD
involved in dentate gyrus development IMP
IMP: Inferred from mutant phenotype
15459104 RGD
involved in hypothalamus development IEP
IEP: Inferred from expression pattern
10436054 RGD
involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
12670697 RGD
involved in memory IEP
IEP: Inferred from expression pattern
17359920 RGD
involved in midgut development IEP
IEP: Inferred from expression pattern
19946030 RGD
involved in neuron migration IMP
IMP: Inferred from mutant phenotype
12670697 RGD
involved in orbitofrontal cortex development IEP
IEP: Inferred from expression pattern
20035841 RGD
involved in response to amino acid IEP
IEP: Inferred from expression pattern
16484373 RGD
involved in response to axon injury IEP
IEP: Inferred from expression pattern
18625290 RGD
involved in response to corticosterone IEP
IEP: Inferred from expression pattern
19477232 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
19499587 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
15166098 RGD
involved in response to fatty acid IEP
IEP: Inferred from expression pattern
19447164 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
20018181 RGD
involved in response to insecticide IEP
IEP: Inferred from expression pattern
16675515 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
19357777 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
17359920 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
18625290 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
16733048 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
19359144 RGD
involved in social behavior IEP
IEP: Inferred from expression pattern
20035841 RGD
involved in spinal cord patterning IEP
IEP: Inferred from expression pattern
14648677 RGD
involved in synaptic vesicle exocytosis EXP
EXP: Inferred from Experiment
24210904 RGD
involved in synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
24210904 RGD
involved in synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
24210904 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
16420448 RGD
located in dendrite IDA
IDA: Inferred from direct assay
19515914 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
18449964 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
19515914 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
11923015 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

reelin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11835 RELN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18151 Reln Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24626 Reln Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Reln NCBI NCBI:5649