PLA2G4F - phospholipase A2 group IVF Gene

Also Known as PLA2G4FZ

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 255189

About PLA2G4F

This gene has 7 transcripts (splice variants), 140 orthologues and 5 paralogues. Biased expression in skin (RPKM 54.3), lung (RPKM 12.6) and 6 other tissues.

Summary

Predicted to enable calcium ion binding activity; calcium-dependent Phospholipase A2 activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in glycerophospholipid catabolic process. Predicted to act upstream of or within several processes, including arachidonic acid secretion; cellular response to antibiotic; and prostaglandin biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol; ruffle membrane; and vesicle. [provided by Alliance of Genome Resources, Apr 2022]

PLA2G4F Products (1)

mRNA Protein Name
NM_213600.4 NP_998765.3 cytosolic phospholipase A2 zeta precursor

PLA2G4F Protein Structure

C2

C2: C2 domain (46 - 125)

PLA2_B

PLA2_B: Lysophospholipase catalytic domain (359 - 577)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 851 a.a.
Protein Preferred Names Protein Names

cytosolic phospholipase A2 zeta

  • cPLA2-zeta

Related Diseases

Diseases Alias
Mahvash Disease

  • Gcgr-Related Hyperglucagonemia

  • MVAH

  • Alpha-Cell Hyperplasia With Glucagonemia

  • Nesidioblastosis, Alpha Cell Hyperplasia, Microglucagonoma, And Nonfunctioning Islet Cell Tumor

  • Nesidioblastosis Alpha Cell Hyperplasia Microglucagonoma And Nonfunctioning Islet Cell Tumor
Inflammatory Bowel Disease 9

  • IBD9
Inflammatory Bowel Disease 1

  • Inflammatory Bowel Disease 1

  • IBD1

  • Crohn Disease-Associated Growth Failure

  • Crohn Disease

  • Regional Enteritis

  • Ulcerative Colitis

  • Crohn Disease-Associated Growth Failure, Susceptibility To

  • Inflammatory Bowel Disease 1, Crohn Disease

  • Bowel Disease, Inflammatory, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10631 PLA2G4F Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PLA2G4F VGNC VGNC:32962
Felis catus PLA2G4F VGNC VGNC:64202
Canis familiaris PLA2G4F VGNC VGNC:44629
Mus musculus PLA2G4F MGD MGI:2685493
Rattus norvegicus PLA2G4F RGD RGD:1593370
Macaca mulatta PLA2G4F VGNC VGNC:76123
Others PLA2G4F NCBI