2. Gene
  3. GPR150 - G protein-coupled receptor 150 Gene

GPR150 - G protein-coupled receptor 150 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PGR11

Gene ID: 285601 | Gene type: protein coding

About GPR150

This gene has 1 transcript (splice variant), 62 orthologues and 16 paralogues.

Summary

This gene encodes an orphan member of the class A rhodopsin-like family of G-protein-coupled receptors (GPCRs). Within the rhodopsin-like family, this gene is a member of the vasopressin-like subfamily that also includes vasopressin and oxytocin receptors. The silencing of this gene, due to promoter methylation, is associated with ovarian Cancer progression. All GPCRs have a transmembrane domain that includes seven transmembrane alpha-helices. A general feature of GPCR signaling is the agonist-induced conformational change in the receptor, leading to activation of the heterotrimeric G protein. The activated G protein then binds to and activates numerous downstream effector proteins, which generate second messengers that mediate a broad range of cellular and physiological processes. [provided by RefSeq, Jul 2017]

GPR150 Products(1)

mRNA Protein Name
NM_199243.3 NP_954713.1 probable G-protein coupled receptor 150

GPR150 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (79 - 352)

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  • 434 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 150

seven transmembrane helix receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05669 GPR150 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR150 VGNC VGNC:72988
Mus musculus GPR150 MGD MGI:2441872
Rattus norvegicus GPR150 RGD RGD:1564729
Felis catus GPR150 VGNC VGNC:102216