Cyp4f4 - cytochrome P450, family 4, subfamily f, polypeptide 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 286904

Summary

Enables arachidonic acid monooxygenase activity; heme binding activity; and leukotriene-B4 20-monooxygenase activity. Involved in leukotriene B4 catabolic process; omega-hydroxylase P450 pathway; and prostaglandin catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human CYP4F11 (Cytochrome P450 family 4 subfamily F member 11) and CYP4F2 (Cytochrome P450 family 4 subfamily F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp4f4 Products (2)

mRNA Protein Name
NM_173123.1 NP_775146.1 cytochrome P450 4F4
NM_173123.1 NP_775146.1 cytochrome P450 4F4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables arachidonate monooxygenase activity IDA
IDA: Inferred from direct assay
14634044 RGD
enables heme binding IDA
IDA: Inferred from direct assay
11980497 RGD
enables leukotriene-B4 20-monooxygenase activity IDA
IDA: Inferred from direct assay
9344476 RGD
Biological Process GO Annotation Evidence References Source
involved in leukotriene B4 catabolic process IDA
IDA: Inferred from direct assay
9344476 RGD
involved in omega-hydroxylase P450 pathway IDA
IDA: Inferred from direct assay
14634044 RGD
involved in prostaglandin catabolic process IDA
IDA: Inferred from direct assay
9344476 RGD
involved in response to 3-methylcholanthrene IEP
IEP: Inferred from expression pattern
19889059 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome P450 4F4

  • CYPIVF4

  • leukotriene-B4 20-monooxygenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03482 CYP4F3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03480 CYP4F2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown