Fcho1 - FCH and mu domain containing endocytic adaptor 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290639

Summary

Predicted to enable AP-2 adaptor complex binding activity. Predicted to be involved in clathrin coat assembly and clathrin-dependent endocytosis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in clathrin-coated pit and clathrin-coated vesicle. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human FCHO1 (FCH and mu domain containing endocytic adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fcho1 Products (1)

mRNA Protein Name
NM_001395712.1 NP_001382641.1 F-BAR domain only protein 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in postsynaptic endocytic zone IDA
IDA: Inferred from direct assay
35072626 RGD
is active in postsynaptic endocytic zone IMP
IMP: Inferred from mutant phenotype
35072626 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-BAR domain only protein 1

  • FCH domain only 1

  • FCH domain only protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04834 FCHO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22504 Fcho1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fcho1 NCBI NCBI:23149