Mpdz - multiple PDZ domain crumbs cell polarity complex component Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29365

Summary

Predicted to enable protein C-terminus binding activity. Involved in myelination. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; apical plasma membrane; and apicolateral plasma membrane. Predicted to be part of subapical complex. Predicted to be active in several cellular components, including apical part of cell; bicellular tight junction; and synapse. Human ortholog(s) of this gene implicated in hydrocephalus. Orthologous to human MPDZ (multiple PDZ domain crumbs cell polarity complex component). [provided by Alliance of Genome Resources, Apr 2022]

Mpdz Products (1)

mRNA Protein Name
NM_019196.1 NP_062069.1 multiple PDZ domain protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19071123 RGD
Biological Process GO Annotation Evidence References Source
involved in myelination IPI
IPI: Inferred from physical interaction
12403818 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
15312654 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
15312654 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

multiple PDZ domain protein

  • multi-PDZ domain protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07732 LNX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08609 MPDZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpdz NCBI NCBI:8777