Atp5mc1 - ATP synthase membrane subunit c locus 1 Gene

Rattus norvegicus

Also known as Atp5g1

Gene ID: 29754 | Gene type: protein coding

About Atp5mc1

Summary

Enables ligand-gated channel activity. Involved in several processes, including cold acclimation; negative regulation of mitochondrial membrane potential; and response to amino acid. Located in distal axon and neuronal cell body. Part of cation channel complex and mitochondrial proton-transporting ATP Synthase complex, coupling factor F(o). Orthologous to human ATP5MC1 (ATP Synthase membrane subunit c locus 1). [provided by Alliance of Genome Resources, Apr 2022]

Atp5mc1 Products(1)

mRNA	Protein	Name
NM_017311.1	NP_059007.1	ATP synthase F(0) complex subunit C1, mitochondrial precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ligand-gated channel activity	IDA IDA: Inferred from direct assay	11588987	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to L-glutamate	IMP IMP: Inferred from mutant phenotype	28777375	RGD
involved in cold acclimation	IEP IEP: Inferred from expression pattern	9163327	RGD
involved in negative regulation of mitochondrial membrane potential	IMP IMP: Inferred from mutant phenotype	28777375	RGD
involved in negative regulation of reactive oxygen species biosynthetic process	IMP IMP: Inferred from mutant phenotype	22209705	RGD
involved in pore complex assembly	IDA IDA: Inferred from direct assay	11588987	RGD
involved in positive regulation of axon extension	IMP IMP: Inferred from mutant phenotype	22209705	RGD
involved in response to 3,3',5-triiodo-L-thyronine	IEP IEP: Inferred from expression pattern	9163327	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	11459924	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of cation channel complex	IDA IDA: Inferred from direct assay	11588987	RGD
located in distal axon	IDA IDA: Inferred from direct assay	22209705	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	22209705	RGD
part of proton-transporting ATP synthase complex	IDA IDA: Inferred from direct assay	17575325	RGD
part of proton-transporting ATP synthase complex, coupling factor F(o)	IDA IDA: Inferred from direct assay	10887193	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ATP synthase F(0) complex subunit C1, mitochondrial

ATP synthase H+ transporting mitochondrial F0 complex subunit c (subunit 9)	ATP synthase lipid-binding protein, mitochondrial
ATP synthase proteolipid P1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
ATP synthase, H+

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01208	ATP5MC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atp5mc1	NCBI	NCBI:516

Name
Email *

	Sorry, but the email address you supplied was invalid.