Rab3gap1 - RAB3 GTPase activating protein catalytic subunit 1 Gene

Also Known as Rab3-GAP; RGD1306487

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 304759

Summary

Enables GTPase activator activity. Predicted to be involved in several processes, including modulation of chemical synaptic transmission; positive regulation of macromolecule metabolic process; and positive regulation of organelle organization. Located in excitatory synapse. Human ortholog(s) of this gene implicated in Warburg micro syndrome 1. Orthologous to human RAB3GAP1 (RAB3 GTPase activating protein catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Rab3gap1 Products (2)

mRNA Protein Name
NM_001402216.2 NP_001389145.1 rab3 GTPase-activating protein catalytic subunit isoform 2
NM_001402314.1 NP_001389243.1 rab3 GTPase-activating protein catalytic subunit isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
9733780 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9733780 RGD
Cellular Component GO Annotation Evidence References Source
located in excitatory synapse IDA
IDA: Inferred from direct assay
19730411 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rab3 GTPase-activating protein catalytic subunit

  • RAB3 GTPase activating protein subunit 1

  • RAB3 GTPase-activating protein 130 kDa subunit

  • rab3-GAP p130

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11559 RAB3GAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab3gap1 NCBI NCBI:22930