2. Gene
  3. Necap1 - NECAP endocytosis associated 1 Gene

Necap1 - NECAP endocytosis associated 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1306053

Gene ID: 312694 | Gene type: protein coding

About Necap1

Summary

Predicted to be involved in endocytosis. Predicted to be located in clathrin-coated pit. Predicted to be part of clathrin vesicle coat. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Orthologous to human NECAP1 (NECAP endocytosis associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Necap1 Products(1)

mRNA Protein Name
NM_001029919.2 NP_001025090.1 adaptin ear-binding coat-associated protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17762867 RGD
Biological Process GO Annotation Evidence Reference Source
involved in presynaptic endocytosis IDA
IDA: Inferred from direct assay
24130457 RGD
involved in presynaptic endocytosis IMP
IMP: Inferred from mutant phenotype
24130457 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in presynapse IDA
IDA: Inferred from direct assay
16879712 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adaptin ear-binding coat-associated protein 1

NECAP endocytosis-associated protein 1

NECAP-1

adaptin ear-binding clathrin-associated protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09172 NECAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Necap1 NCBI NCBI:25977