Sbf2 - SET binding factor 2 Gene

Also Known as Mtmr13; mMTMH1; 4833411B01Rik; B430219L04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 319934

Summary

Enables several functions, including identical protein binding activity; Phosphatase binding activity; and Phosphatase regulator activity. Predicted to be involved in regulation of GTPase activity. Predicted to act upstream of or within Autophagy. Located in vacuolar membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and sciatic nerve. Used to study Charcot-Marie-Tooth disease type 4B2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4B2. Orthologous to human SBF2 (SET binding factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sbf2 Products (4)

mRNA Protein Name
NM_001404387.1 NP_001391316.1 myotubularin-related protein 13 isoform 2
NM_001404388.1 NP_001391317.1 myotubularin-related protein 13 isoform 3
NM_001404389.1 NP_001391318.1 myotubularin-related protein 13 isoform 4
NM_177324.3 NP_796298.2 myotubularin-related protein 13 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16399794 MGI
enables phosphatase binding IPI
IPI: Inferred from physical interaction
16399794 MGI
enables phosphatase regulator activity IDA
IDA: Inferred from direct assay
16399794 MGI
enables phosphatidylinositol binding IDA
IDA: Inferred from direct assay
16399794 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16399794 MGI
Cellular Component GO Annotation Evidence References Source
located in vacuolar membrane IDA
IDA: Inferred from direct assay
16399794 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myotubularin-related protein 13

  • inactive phosphatidylinositol 3-phosphatase 13

  • myotubularin related protein 13

  • myotubularin-related protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12465 SBF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sbf2 NCBI NCBI:81846