Ppfia2 - protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 Gene

Also Known as mKIAA4112; 5330438O12; B230207K17Rik; E130120L08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 327814

Summary

Predicted to be a structural constituent of presynapse. Predicted to be involved in several processes, including dense core granule cytoskeletal transport; regulation of dendritic spine morphogenesis; and regulation of synaptic vesicle exocytosis. Is active in glutamatergic synapse and presynaptic cytosol. Is expressed in several structures, including adrenal gland; brain; pancreas; retina layer; and testis. Orthologous to human PPFIA2 (PTPRF interacting protein alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Ppfia2 Products (29)

mRNA Protein Name
NM_001205341.1 NP_001192270.1 liprin-alpha-2 isoform 1
NM_001359672.1 NP_001346601.1 liprin-alpha-2 isoform 3
NM_001359673.1 NP_001346602.1 liprin-alpha-2 isoform 4
NM_001359674.1 NP_001346603.1 liprin-alpha-2 isoform 5
NM_001359675.1 NP_001346604.1 liprin-alpha-2 isoform 6
NM_001359676.1 NP_001346605.1 liprin-alpha-2 isoform 7
NM_001359677.1 NP_001346606.1 liprin-alpha-2 isoform 8
NM_001359678.1 NP_001346607.1 liprin-alpha-2 isoform 9
NM_001359679.1 NP_001346608.1 liprin-alpha-2 isoform 10
NM_001359680.1 NP_001346609.1 liprin-alpha-2 isoform 11
NM_001359681.1 NP_001346610.1 liprin-alpha-2 isoform 12
NM_001359682.1 NP_001346611.1 liprin-alpha-2 isoform 13
NM_001359683.1 NP_001346612.1 liprin-alpha-2 isoform 14
NM_001359684.1 NP_001346613.1 liprin-alpha-2 isoform 15
NM_001359685.1 NP_001346614.1 liprin-alpha-2 isoform 16
NM_001359686.1 NP_001346615.1 liprin-alpha-2 isoform 17
NM_001359687.1 NP_001346616.1 liprin-alpha-2 isoform 18
NM_001359688.1 NP_001346617.1 liprin-alpha-2 isoform 19
NM_001359689.1 NP_001346618.1 liprin-alpha-2 isoform 20
NM_001359690.1 NP_001346619.1 liprin-alpha-2 isoform 21
NM_001359691.1 NP_001346620.1 liprin-alpha-2 isoform 22
NM_001359692.1 NP_001346621.1 liprin-alpha-2 isoform 23
NM_001359693.1 NP_001346622.1 liprin-alpha-2 isoform 24
NM_001359694.1 NP_001346623.1 liprin-alpha-2 isoform 25
NM_001359695.1 NP_001346624.1 liprin-alpha-2 isoform 26
NM_001359696.1 NP_001346625.1 liprin-alpha-2 isoform 27
NM_001359697.1 NP_001346626.1 liprin-alpha-2 isoform 28
NM_001359698.1 NP_001346627.1 liprin-alpha-2 isoform 29
NM_177373.4 NP_796347.2 liprin-alpha-2 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16186258 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
23791195 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29439199 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
29439199 MGI
is active in synapse IDA
IDA: Inferred from direct assay
21618221 MGI
located in synapse IDA
IDA: Inferred from direct assay
16186258 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liprin-alpha-2

  • PTPRF interacting protein alpha 2

  • protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10940 PPFIA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppfia2 NCBI NCBI:8499