Gjd3 - gap junction protein, delta 3 Gene

Also Known as Cxnr; Gjc1; Gja11; cx30.2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 353155

Summary

Enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling and ion channel activity. Involved in negative regulation of cell communication by electrical coupling involved in cardiac conduction and regulation of heart contraction. Located in gap junction. Part of connexin complex. Is expressed in heart. Orthologous to human GJD3 (Gap Junction Protein delta 3). [provided by Alliance of Genome Resources, Apr 2022]

Gjd3 Products (1)

mRNA Protein Name
NM_178596.3 NP_848711.2 gap junction delta-3 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling IMP
IMP: Inferred from mutant phenotype
22982984 MGI
enables monoatomic ion channel activity IDA
IDA: Inferred from direct assay
15879306 MGI
enables monoatomic ion channel activity IGI
IGI: Inferred from genetic interaction
15879306 MGI
Biological Process GO Annotation Evidence References Source
involved in AV node cell to bundle of His cell communication by electrical coupling IMP
IMP: Inferred from mutant phenotype
16571663 MGI
involved in negative regulation of cardiac conduction IMP
IMP: Inferred from mutant phenotype
16571663 MGI
involved in negative regulation of cell communication by electrical coupling involved in cardiac conduction IMP
IMP: Inferred from mutant phenotype
16571663 MGI
involved in negative regulation of heart rate IMP
IMP: Inferred from mutant phenotype
16571663 MGI
Cellular Component GO Annotation Evidence References Source
part of connexin complex IGI
IGI: Inferred from genetic interaction
15879306 MGI
located in gap junction IDA
IDA: Inferred from direct assay
12681499 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction delta-3 protein

  • connexin 30.2

  • connexin r

  • gap junction alpha-11 protein

  • gap junction chi-1 protein

  • gap junction membrane channel protein chi 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05456 GJD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjd3 NCBI NCBI:125111