Prrt2 - proline-rich transmembrane protein 2 Gene

Also Known as DSPB3; RGD1564195

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361651

Summary

Enables SH3 domain binding activity. Predicted to be involved in negative regulation of SNARE complex assembly; negative regulation of short-term synaptic potentiation; and synaptic vesicle exocytosis. Predicted to act upstream of or within neuromuscular process controlling posture. Located in neuron projection. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and episodic kinesigenic dyskinesia 1. Orthologous to human PRRT2 (proline rich transmembrane protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Prrt2 Products (1)

mRNA Protein Name
NM_001276470.1 NP_001263399.1 proline-rich transmembrane protein 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
26797119 RGD
Cellular Component GO Annotation Evidence References Source
located in neuron projection IDA
IDA: Inferred from direct assay
26797119 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline-rich transmembrane protein 2

  • Dispanin subfamily B member 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11242 PRRT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prrt2 NCBI NCBI:112476