Nme8 - NME/NM23 family member 8 Gene

Also Known as Sptrx2; Txndc3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 364729

Summary

Predicted to enable microtubule binding activity. Predicted to be involved in cilium assembly. Predicted to act upstream of or within cellular response to Reactive Oxygen Species and flagellated sperm motility. Located in sperm fibrous sheath. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 6. Orthologous to human NME8 (NME/NM23 family member 8). [provided by Alliance of Genome Resources, Apr 2022]

Nme8 Products (1)

mRNA Protein Name
NM_198792.3 NP_942087.2 thioredoxin domain-containing protein 3

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in sperm fibrous sheath IDA
IDA: Inferred from direct assay
12909633 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 3

  • spermatid-specific thioredoxin-2 protein

  • sptrx-2

  • thioredoxin domain containing 3 (spermatozoa)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09379 NME8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nme8 NCBI NCBI:51314