MELK - maternal embryonic leucine zipper kinase Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 481608
About MELK
Primary_assembly 11: 54,080,479-54,176,384 forward strand.ROS_Cfam_1.0:CM025110.1
This gene has 9 transcripts (splice variants), 217 orthologues and 19 paralogues.
MELK Products (16)
| mRNA | Protein | Name |
|---|---|---|
| XM_038682162.1 | XP_038538090.1 | maternal embryonic leucine zipper kinase isoform X4 |
| XM_038682158.1 | XP_038538086.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682160.1 | XP_038538088.1 | maternal embryonic leucine zipper kinase isoform X2 |
| XM_038682164.1 | XP_038538092.1 | maternal embryonic leucine zipper kinase isoform X5 |
| XM_038682163.1 | XP_038538091.1 | maternal embryonic leucine zipper kinase isoform X4 |
| XM_038682161.1 | XP_038538089.1 | maternal embryonic leucine zipper kinase isoform X3 |
| XM_038682157.1 | XP_038538085.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682156.1 | XP_038538084.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682163.1 | XP_038538091.1 | maternal embryonic leucine zipper kinase isoform X4 |
| XM_038682156.1 | XP_038538084.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682160.1 | XP_038538088.1 | maternal embryonic leucine zipper kinase isoform X2 |
| XM_038682164.1 | XP_038538092.1 | maternal embryonic leucine zipper kinase isoform X5 |
| XM_038682161.1 | XP_038538089.1 | maternal embryonic leucine zipper kinase isoform X3 |
| XM_038682157.1 | XP_038538085.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682158.1 | XP_038538086.1 | maternal embryonic leucine zipper kinase isoform X1 |
| XM_038682162.1 | XP_038538090.1 | maternal embryonic leucine zipper kinase isoform X4 |
MELK Protein Structure
STKc_MELK
STKc_MELK: cd14078 (6 - 262)
UBA_MELK
UBA_MELK: cd14341 (280 - 331)
MELK_C
MELK_C: cd12198 (554 - 648)
- 0
- 100
- 200
- 300
- 400
- 500
- 600
- 651 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
maternal embryonic leucine zipper kinase |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15512 | OTSSP167 | Inhibitor | 99.27% | Phase 2 |
| HY-15512A | OTSSP167 hydrochloride | Inhibitor | 99.78% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(10)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-100368A | MELK-8a hydrochloride | Inhibitor | 99.31% | Unkown |
| HY-148065 | FMF-06-098-1 | Inhibitor | 98.77% | Unkown |
| HY-101515 | MELK-IN-1 | Inhibitor | 98.03% | Unkown |
| HY-12420 | JNJ-47117096 hydrochloride | Inhibitor | 99.67% | Unkown |
| HY-122665 | HTH-01-091 | Inhibitor | 99.81% | Unkown |
| HY-100368 | MELK-8a | Inhibitor | 98.32% | Unkown |
| HY-122665A | HTH-01-091 TFA | Inhibitor | 99.48% | Unkown |
| HY-155748 | Antitumor agent-116 | Inhibitor | / | Unkown |
| HY-N17632 | Moracin G | Inhibitor | / | Unkown |
| HY-12420A | JNJ-47117096 | Inhibitor | / | Unkown |
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