2. Gene
  3. MELK - maternal embryonic leucine zipper kinase Gene

MELK - maternal embryonic leucine zipper kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 481608 | Gene type: protein coding

About MELK

Primary_assembly 11: 54,080,479-54,176,384 forward strand.ROS_Cfam_1.0:CM025110.1

This gene has 9 transcripts (splice variants), 217 orthologues and 19 paralogues.

MELK Products(16)

mRNA Protein Name
XM_038682162.1 XP_038538090.1 maternal embryonic leucine zipper kinase isoform X4
XM_038682158.1 XP_038538086.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682160.1 XP_038538088.1 maternal embryonic leucine zipper kinase isoform X2
XM_038682164.1 XP_038538092.1 maternal embryonic leucine zipper kinase isoform X5
XM_038682163.1 XP_038538091.1 maternal embryonic leucine zipper kinase isoform X4
XM_038682161.1 XP_038538089.1 maternal embryonic leucine zipper kinase isoform X3
XM_038682157.1 XP_038538085.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682156.1 XP_038538084.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682163.1 XP_038538091.1 maternal embryonic leucine zipper kinase isoform X4
XM_038682156.1 XP_038538084.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682160.1 XP_038538088.1 maternal embryonic leucine zipper kinase isoform X2
XM_038682164.1 XP_038538092.1 maternal embryonic leucine zipper kinase isoform X5
XM_038682161.1 XP_038538089.1 maternal embryonic leucine zipper kinase isoform X3
XM_038682157.1 XP_038538085.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682158.1 XP_038538086.1 maternal embryonic leucine zipper kinase isoform X1
XM_038682162.1 XP_038538090.1 maternal embryonic leucine zipper kinase isoform X4

MELK Protein Structure

STKc_MELK

STKc_MELK: cd14078 (6 - 262)

UBA_MELK

UBA_MELK: cd14341 (280 - 331)

MELK_C

MELK_C: cd12198 (554 - 648)

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  • 651 a.a.
Protein Preferred Names Protein Names

maternal embryonic leucine zipper kinase

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-15512 OTSSP167 Inhibitor 99.27% Phase 2
HY-15512A OTSSP167 hydrochloride Inhibitor 99.78% Phase 2
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100368A MELK-8a hydrochloride Inhibitor 99.31% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-101515 MELK-IN-1 Inhibitor 98.03% Unkown
HY-12420 JNJ-47117096 hydrochloride Inhibitor 99.67% Unkown
HY-122665 HTH-01-091 Inhibitor 99.81% Unkown
HY-100368 MELK-8a Inhibitor 98.32% Unkown
HY-122665A HTH-01-091 TFA Inhibitor 99.48% Unkown
HY-155748 Antitumor agent-116 Inhibitor / Unkown
HY-N17632 Moracin G Inhibitor / Unkown
HY-12420A JNJ-47117096 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MELK NCBI NCBI:9833