S1PR5 - sphingosine-1-phosphate receptor 5 Gene

Also Known as EDG8

Species: Bos taurus

Gene Type: protein coding
Gene ID: 517533

About S1PR5

Primary_assembly 7: 15,021,733-15,025,832 reverse strand.ARS-UCD1.2:CM008174.2

This gene has 1 transcript (splice variant), 236 orthologues and 19 paralogues.

S1PR5 Products (1)

mRNA Protein Name
NM_001192475.1 NP_001179404.1 sphingosine 1-phosphate receptor 5

S1PR5 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (37 - 317)

7tm_GPCRs

7tm_GPCRs: cd14964 (39 - 63)

7tm_GPCRs

7tm_GPCRs: cd14964 (72 - 93)

7tm_GPCRs

7tm_GPCRs: cd14964 (109 - 131)

7tm_GPCRs

7tm_GPCRs: cd14964 (153 - 169)

7tm_GPCRs

7tm_GPCRs: cd14964 (190 - 213)

7tm_GPCRs

7tm_GPCRs: cd14964 (250 - 272)

7tm_GPCRs

7tm_GPCRs: cd14964 (285 - 310)

  • 0
  • 100
  • 200
  • 300
  • 399 a.a.
Protein Preferred Names Protein Names

sphingosine 1-phosphate receptor 5

  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 8

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12355 Siponimod Agonist 99.95% Yes
HY-12288 Ozanimod Agonist 99.98% Yes
HY-10569 Ponesimod Agonist 99.78% Yes
HY-12288A Ozanimod hydrochloride Modulator 98.10% Yes
HY-12355A Siponimod hemifumarate Agonist 99.64% Yes

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-17606 Cenerimod Agonist 99.43% Phase 3

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111253 CYM-5478 Agonist 99.90% Unkown
HY-136578 RP101988 Agonist 98.80% Unkown
HY-176533 S1PR5-IN-1 Inhibitor 99.58% Unkown
HY-136576 RP101075 Agonist 99.19% Unkown
HY-148115 S1p receptor agonist 2 Agonist / Unkown
HY-148198 S1P5 receptor agonist-1 Agonist / Unkown
HY-136577 RP101442 Agonist / Unkown
HY-14402 AMG 369 Agonist / Unkown
HY-181875 S1PR1/S1PR5 agonist-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S1PR5 NCBI NCBI:53637