2. Gene
  3. Diaph2 - diaphanous related formin 2 Gene

Diaph2 - diaphanous related formin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Dia3; Drf2; Diap2; E430022I22Rik

Gene ID: 54004 | Gene type: protein coding

About Diaph2

Summary

Enables actin binding activity. Acts upstream of or within actin filament polymerization. Predicted to be located in endoplasmic reticulum and nucleolus. Is expressed in brain. Human ortholog(s) of this gene implicated in primary ovarian insufficiency and primary ovarian insufficiency 2A. Orthologous to human DIAPH2 (diaphanous related formin 2). [provided by Alliance of Genome Resources, Apr 2022]

Diaph2 Products(1)

mRNA Protein Name
NM_172493.2 NP_766081.1 protein diaphanous homolog 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables actin binding IDA
IDA: Inferred from direct assay
14992721 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21278336 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within actin filament polymerization IDA
IDA: Inferred from direct assay
14992721 MGI
acts upstream of or within axon midline choice point recognition IGI
IGI: Inferred from genetic interaction
23890216 MGI
acts upstream of or within ephrin receptor signaling pathway IGI
IGI: Inferred from genetic interaction
23890216 MGI
acts upstream of or within multicellular organismal locomotion IGI
IGI: Inferred from genetic interaction
23890216 MGI
acts upstream of or within negative regulation of neuron projection regeneration IGI
IGI: Inferred from genetic interaction
23890216 MGI
acts upstream of or within neuron projection retraction IGI
IGI: Inferred from genetic interaction
23890216 MGI
acts upstream of or within protein localization IGI
IGI: Inferred from genetic interaction
23890216 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein diaphanous homolog 2

diaphanous homolog 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03764 DIAPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Diaph2 NCBI NCBI:1730