SASH3 - SAM and SH3 domain containing 3 Gene
Also Known as SLY; 753P9; HACS2; CXorf9; IMD102; SH3D6C
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 54440
About SASH3
Cytogenetic location: Xq26.1
Genomic coordinates (GRCh38): X:129,779,949-129,795,201 (from NCBI)
This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in lymph node (RPKM 60.1), spleen (RPKM 41.7) and 11 other tissues.
Summary
The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009]
SASH3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_018990.4 | NP_061863.1 | SAM and SH3 domain-containing protein 3 |
SASH3 Protein Structure
SLY
SLY: Lymphocyte signaling adaptor protein (19 - 174)
SH3_2
SH3_2: Variant SH3 domain (177 - 229)
SAM_2
SAM_2: SAM domain (Sterile alpha motif) (253 - 313)
- 0
- 100
- 200
- 300
- 380 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
SAM and SH3 domain-containing protein 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Immunodeficiency 102 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS12453 | SASH3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | SASH3 | VGNC | VGNC:77022 |
| Felis catus | SASH3 | VGNC | VGNC:64879 |
| Bos taurus | SASH3 | VGNC | VGNC:34294 |
| Mus musculus | SASH3 | MGD | MGI:1921381 |
| Canis familiaris | SASH3 | VGNC | VGNC:45872 |
| Rattus norvegicus | SASH3 | RGD | RGD:1560293 |
| Others | SASH3 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service