STOX2 - storkhead box 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56977

About STOX2

Cytogenetic location: 4q35.1 Genomic coordinates (GRCh38): 4:183,798,022-184,023,530 (from NCBI)

This gene has 5 transcripts (splice variants), 278 orthologues and 1 paralogue. Broad expression in brain (RPKM 5.4), thyroid (RPKM 2.4) and 22 other tissues.

Summary

This gene encodes a Storkhead-box_winged-helix domain containing protein. This protein is differentially expressed in decidual tissue and may be involved in the susceptibility to pre-eclampsia with fetal growth restriction. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

STOX2 Products (1)

mRNA Protein Name
NM_020225.3 NP_064610.1 storkhead-box protein 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in embryo development ending in birth or egg hatching IEP
IEP: Inferred from expression pattern
20643876 GOA
involved in maternal placenta development IEP
IEP: Inferred from expression pattern
20643876 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STOX2 Protein Structure

Stork_head

Stork_head: Winged helix Storkhead-box1 domain (63 - 142)

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  • 926 a.a.
Protein Preferred Names Protein Names

storkhead-box protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13955 STOX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus STOX2 VGNC VGNC:65797
Canis familiaris STOX2 VGNC VGNC:46934
Rattus norvegicus STOX2 RGD RGD:708477
Macaca mulatta STOX2 VGNC VGNC:78210
Mus musculus STOX2 MGD MGI:1918319
Bos taurus STOX2 VGNC VGNC:35415
Others STOX2 NCBI