2. Gene
  3. Tob2 - transducer of ERBB2, 2 Gene

Tob2 - transducer of ERBB2, 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1663; 2900090N22Rik; 4930545K18Rik

Gene ID: 57259 | Gene type: protein coding

About Tob2

Summary

Enables vitamin D receptor binding activity. Acts upstream of or within negative regulation of osteoclast differentiation; positive regulation of ossification; and regulation of gene expression. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including Meckel's cartilage; genitourinary system; liver; orbito-sphenoid; and spleen. Orthologous to human TOB2 (transducer of ERBB2, 2). [provided by Alliance of Genome Resources, Apr 2022]

Tob2 Products(1)

mRNA Protein Name
NM_020507.3 NP_065253.1 protein Tob2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables nuclear vitamin D receptor binding IPI
IPI: Inferred from physical interaction
18358842 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
18358842 MGI
acts upstream of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
18358842 MGI
acts upstream of or within positive regulation of ossification IMP
IMP: Inferred from mutant phenotype
18358842 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18358842 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Tob2

transducer of erbB-2 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14873 TOB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tob2 NCBI NCBI:10766