2. Gene
  3. PCIF1 - phosphorylated CTD interacting factor 1 Gene

PCIF1 - phosphorylated CTD interacting factor 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CAPAM; hCAPAM; hPCIF1; C20orf67; PPP1R121

Gene ID: 63935 | Gene type: protein coding

About PCIF1

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:45,934,683-45,948,020 (from NCBI)

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in ovary (RPKM 21.7), thyroid (RPKM 17.5) and 25 other tissues.

Summary

Enables RNA polymerase II C-terminal domain phosphoserine binding activity; S-adenosyl-L-methionine binding activity; and mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Involved in mRNA methylation; negative regulation of translation; and positive regulation of translation. Located in intercellular bridge; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PCIF1 Products(1)

mRNA Protein Name
NM_022104.4 NP_071387.1 mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase

PCIF1 Protein Structure

WW

WW: WW domain (48 - 75)

PCIF1_WW

PCIF1_WW: Phosphorylated CTD interacting factor 1 WW domain (446 - 621)

  • 0
  • 200
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  • 600
  • 704 a.a.
Protein Preferred Names Protein Names

mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase

PDX-1 C terminus-interacting factor 1

Related Diseases

Diseases Alias
Childhood Supratentorial Ependymoma

Paediatric Cerebral Ependymoma

Paediatric Supratentorial Ependymoblastoma

Paediatric Supratentorial Ependymoma

Pediatric Cerebral Ependymoma

Pediatric Supratentorial Ependymoblastoma

Pediatric Supratentorial Ependymoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10151 PCIF1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PCIF1 RGD RGD:1310800
Mus musculus PCIF1 MGD MGI:2443858
Bos taurus PCIF1 VGNC VGNC:32630
Canis familiaris PCIF1 VGNC VGNC:44306
Macaca mulatta PCIF1 VGNC VGNC:75621
Felis catus PCIF1 VGNC VGNC:81142