2. Gene
  3. Mcoln2 - mucolipin 2 Gene

Mcoln2 - mucolipin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TRPML2; 3300002C04Rik

Gene ID: 68279 | Gene type: protein coding

About Mcoln2

Summary

Enables identical protein binding activity. Acts upstream of or within myeloid leukocyte migration and positive regulation of chemokine production. Located in recycling endosome. Is expressed in cochlea. Orthologous to human MCOLN2 (mucolipin TRP cation channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Mcoln2 Products(2)

mRNA Protein Name
NM_001005846.2 NP_001005846.1 mucolipin-2 isoform 2
NM_026656.5 NP_080932.2 mucolipin-2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
26432893 MGI
enables iron ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
18794901 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within macrophage migration IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within neutrophil migration IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within positive regulation of chemokine (C-C motif) ligand 5 production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within positive regulation of chemokine (C-X-C motif) ligand 2 production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within positive regulation of chemokine production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within positive regulation of macrophage inflammatory protein 1 alpha production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within positive regulation of monocyte chemotactic protein-1 production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
acts upstream of or within regulation of chemokine (C-X-C motif) ligand 2 production IMP
IMP: Inferred from mutant phenotype
26432893 MGI
Cellular Component GO Annotation Evidence Reference Source
located in recycling endosome IDA
IDA: Inferred from direct assay
26432893 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucolipin-2

mucolipidin 2

transient receptor potential channel mucolipin 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08245 MCOLN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcoln2 NCBI NCBI:255231