Prdm12 - PR/SET domain 12 Gene

Predicted to enable Histone Methyltransferase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; neurogenesis; and positive regulation of histone H3-K9 dimethylation. Predicted to act upstream of or within detection of temperature stimulus involved in sensory perception of pain; neuron projection development; and positive regulation of histone H3-K9 methylation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 8. Orthologous to human PRDM12 (PR/SET domain 12). [provided by Alliance of Genome Resources, Apr 2022]