Lsm11 - U7 snRNP-specific Sm-like protein LSM11 Gene

Mus musculus

Also known as 2210404M20Rik

Gene ID: 72290 | Gene type: protein coding

About Lsm11

Summary

Predicted to enable U7 snRNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Part of U7 snRNP and histone pre-mRNA 3'end processing complex. Is expressed in femur; nucleus pulposus; rib; thoracic segment skeleton; and turbinate bone primordium. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human LSM11 (LSM11, U7 small nuclear RNA associated). [provided by Alliance of Genome Resources, Apr 2022]

Lsm11 Products(1)

mRNA	Protein	Name
NM_028185.2	NP_082461.1	U7 snRNA-associated Sm-like protein LSm11

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16087681	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in mRNA 3'-end processing by stem-loop binding and cleavage	IDA IDA: Inferred from direct assay	12975319	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of U7 snRNP	IDA IDA: Inferred from direct assay	12975319	MGI
part of histone pre-mRNA 3'end processing complex	IDA IDA: Inferred from direct assay	19470752	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

U7 snRNA-associated Sm-like protein LSm11

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07854	LSM11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Lsm11	NCBI	NCBI:134353

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