2. Gene
  3. Calb1 - calbindin 1 Gene

Calb1 - calbindin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CaBP28K

Gene ID: 83839 | Gene type: protein coding

About Calb1

Summary

Enables calcium ion binding activity. Involved in several processes, including cochlea development; regulation of presynaptic cytosolic calcium ion concentration; and regulation of synaptic plasticity. Located in several cellular components, including cuticular plate; dendritic spine; and stereocilium. Is active in calyx of Held; postsynaptic cytosol; and presynaptic cytosol. Biomarker of bilirubin metabolic disorder. Orthologous to human CALB1 (calbindin 1). [provided by Alliance of Genome Resources, Apr 2022]

Calb1 Products(1)

mRNA Protein Name
NM_031984.2 NP_114190.1 calbindin
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
19658395 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cochlea development IEP
IEP: Inferred from expression pattern
16120789 RGD
involved in learning or memory IEP
IEP: Inferred from expression pattern
15318329 RGD
involved in regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
15318329 RGD
involved in response to auditory stimulus IEP
IEP: Inferred from expression pattern
22428005 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
11724816 RGD
is active in calyx of Held IDA
IDA: Inferred from direct assay
15355314 RGD
located in cuticular plate IDA
IDA: Inferred from direct assay
16120789 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
15809430 RGD
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
15809430 RGD
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
15355314 RGD
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
12528187 RGD
located in stereocilium IDA
IDA: Inferred from direct assay
16120789 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calbindin

D-28K

calbindin 1, 28 kD

calbindin D28

cerebellar Ca-binding protein, spot 35 protein

spot 35 protein

vitamin D-dependent calcium-binding protein, avian-type

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01826 CALB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Calb1 NCBI NCBI:793