H1-10 - H1.10 linker histone Gene

Also Known as H1X; H1FX; H1.10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8971

About H1-10

Cytogenetic location: 3q21.3 Genomic coordinates (GRCh38): 3:129,314,771-129,316,286 (from NCBI)

This gene has 2 transcripts (splice variants), 119 orthologues and 9 paralogues.

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]

H1-10 Products (1)

mRNA Protein Name
NM_006026.4 NP_006017.1 histone H1.10

H1-10 Protein Structure

Linker_histone

Linker_histone: linker histone H1 and H5 family (47 - 117)

  • 0
  • 100
  • 200
  • 213 a.a.
Protein Preferred Names Protein Names

histone H1.10

  • H1 histone family member X

Related Diseases

Diseases Alias
Animal Phobia

  • Zoophobia

  • Fear Of Animals
Epithelial-Stromal Tgfbi Dystrophy
Lattice Corneal Dystrophy

  • Familial Amyloid Neuropathy, Finnish Type

  • Familial Amyloid Polyneuropathy, Type V
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05946 H1-10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus H1-10 VGNC VGNC:109865
Rattus norvegicus H1-10 RGD RGD:1565596
Macaca mulatta H1-10 VGNC VGNC:109751
Mus musculus H1-10 MGD MGI:2685307
Bos taurus H1-10 VGNC VGNC:83614
Others H1-10 NCBI