DHRS3 - dehydrogenase/reductase 3 Gene

Also Known as SDR1; RDH17; Rsdr1; DD83.1; SDR16C1; retSDR1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9249

About DHRS3

Cytogenetic location: 1p36.21 Genomic coordinates (GRCh38): 1:12,567,910-12,618,210 (from NCBI)

This gene has 4 transcripts (splice variants), 225 orthologues, 25 paralogues and is associated with 1 phenotype. Ubiquitous expression in liver (RPKM 41.2), fat (RPKM 39.1) and 25 other tissues.

Summary

Short-chain dehydrogenases/reductases (SDRs), such as DHRS3, catalyze the oxidation/reduction of a wide range of substrates, including retinoids and Steroids (Haeseleer and Palczewski, 2000 [PubMed 10800688]).[supplied by OMIM, Jun 2009]

DHRS3 Products (3)

mRNA Protein Name
NM_001319225.2 NP_001306154.1 short-chain dehydrogenase/reductase 3 isoform 2
NM_001324370.2 NP_001311299.1 short-chain dehydrogenase/reductase 3 isoform 2
NM_004753.7 NP_004744.2 short-chain dehydrogenase/reductase 3 isoform 1

DHRS3 Protein Structure

adh_short

adh_short: short chain dehydrogenase (40 - 203)

  • 0
  • 100
  • 200
  • 302 a.a.
Protein Preferred Names Protein Names

short-chain dehydrogenase/reductase 3

  • dehydrogenase/reductase (SDR family) member 3

Related Diseases

Diseases Alias
Neuroblastoma

  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma
Amphetamine Abuse
Microphthalmia, Syndromic 9

  • Matthew-Wood Syndrome

  • Spear Syndrome

  • Anophthalmia/Microphthalmia And Pulmonary Hypoplasia

  • Microphthalmia, Isolated, With Coloboma 8

  • MCOPS9

  • Anophthalmia, Clinical, With Mild Facial Dysmorphism And Variable Malformations Of The Lung, Heart, And Diaphragm

  • Pulmonary Hypoplasia-Diaphragmatic Hernia-Anophthalmia-Cardiac Defect

  • Pdac

  • Pulmonary Agenesis, Microphthalmia, And Diaphragmatic Defect

  • Pmd

  • Syndromic Microphthalmia 9

  • Anophthalmia-Pulmonary Hypoplasia Syndrome

  • Clinical Anophthalmia Mild Facial Dysmorphism Lung Heart And Diaphragm Malformations

  • Pulmonary Agenesis Microphthalmi And Diaphragmatic Defect

  • Microphthalmia Syndromic 9

  • Matthew Wood Syndrome

  • Pdac Syndrome

  • Pulmonary Hypoplasia-Diaphragmatic Hernia-Anophthalmia-Cardiac Defect Syndrome

  • Microphthalmia, Isolated, With Coloboma, 8

  • MCOPCB8

  • Isolated Colobomatous Microphthalmia 8

  • Microphthalmia, Syndromic, 9

  • Anophthalmia With Pulmonary Hypoplasia

  • Microphthalmia Syndromic, Type 9

  • Anophthalmia And Pulmonary Hypoplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03741 DHRS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20392 Dhrs3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26901 Dhrs3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta DHRS3 VGNC VGNC:71649
Rattus norvegicus DHRS3 RGD RGD:1305584
Felis catus DHRS3 VGNC VGNC:61470
Bos taurus DHRS3 VGNC VGNC:97260
Mus musculus DHRS3 MGD MGI:1315215
Canis familiaris DHRS3 VGNC VGNC:39934
Others DHRS3 NCBI