Rbfox2 - RNA binding protein, fox-1 homolog (C. elegans) 2 Gene
Also Known as Fxh; Fbm2; Rbm9; Hrnbp2
Species: Mus musculus
Gene Type: protein coding
Gene ID: 93686
Summary
Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of definitive erythrocyte differentiation. Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; nervous system development; and regulation of heart rate by cardiac conduction. Located in nucleus. Is expressed in several structures, including blastocyst; brain; dorsal root ganglion; early embryo; and limb. Orthologous to human RBFOX2 (RNA binding fox-1 homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Rbfox2 Products (37)
| mRNA | Protein | Name |
|---|---|---|
| NM_001110827.3 | NP_001104297.1 | RNA binding protein fox-1 homolog 2 isoform 3 |
| NM_001110828.3 | NP_001104298.1 | RNA binding protein fox-1 homolog 2 isoform 4 |
| NM_001110829.3 | NP_001104299.1 | RNA binding protein fox-1 homolog 2 isoform 5 |
| NM_001110830.3 | NP_001104300.1 | RNA binding protein fox-1 homolog 2 isoform 6 |
| NM_001286417.2 | NP_001273346.1 | RNA binding protein fox-1 homolog 2 isoform 7 |
| NM_001286418.2 | NP_001273347.1 | RNA binding protein fox-1 homolog 2 isoform 8 |
| NM_001286419.2 | NP_001273348.1 | RNA binding protein fox-1 homolog 2 isoform 9 |
| NM_001358770.2 | NP_001345699.1 | RNA binding protein fox-1 homolog 2 isoform 10 |
| NM_001358772.2 | NP_001345701.1 | RNA binding protein fox-1 homolog 2 isoform 12 |
| NM_001412007.1 | NP_001398936.1 | RNA binding protein fox-1 homolog 2 isoform 13 |
| NM_001412008.1 | NP_001398937.1 | RNA binding protein fox-1 homolog 2 isoform 14 |
| NM_001412009.1 | NP_001398938.1 | RNA binding protein fox-1 homolog 2 isoform 15 |
| NM_001412010.1 | NP_001398939.1 | RNA binding protein fox-1 homolog 2 isoform 16 |
| NM_001412011.1 | NP_001398940.1 | RNA binding protein fox-1 homolog 2 isoform 12 |
| NM_001412012.1 | NP_001398941.1 | RNA binding protein fox-1 homolog 2 isoform 17 |
| NM_001412013.1 | NP_001398942.1 | RNA binding protein fox-1 homolog 2 isoform 18 |
| NM_001412014.1 | NP_001398943.1 | RNA binding protein fox-1 homolog 2 isoform 19 |
| NM_001412015.1 | NP_001398944.1 | RNA binding protein fox-1 homolog 2 isoform 20 |
| NM_001412016.1 | NP_001398945.1 | RNA binding protein fox-1 homolog 2 isoform 21 |
| NM_001412017.1 | NP_001398946.1 | RNA binding protein fox-1 homolog 2 isoform 22 |
| NM_001412018.1 | NP_001398947.1 | RNA binding protein fox-1 homolog 2 isoform 23 |
| NM_001412019.1 | NP_001398948.1 | RNA binding protein fox-1 homolog 2 isoform 24 |
| NM_001412020.1 | NP_001398949.1 | RNA binding protein fox-1 homolog 2 isoform 25 |
| NM_001412021.1 | NP_001398950.1 | RNA binding protein fox-1 homolog 2 isoform 26 |
| NM_001412022.1 | NP_001398951.1 | RNA binding protein fox-1 homolog 2 isoform 27 |
| NM_001412023.1 | NP_001398952.1 | RNA binding protein fox-1 homolog 2 isoform 28 |
| NM_001412024.1 | NP_001398953.1 | RNA binding protein fox-1 homolog 2 isoform 29 |
| NM_001412025.1 | NP_001398954.1 | RNA binding protein fox-1 homolog 2 isoform 30 |
| NM_001412026.1 | NP_001398955.1 | RNA binding protein fox-1 homolog 2 isoform 31 |
| NM_001412027.1 | NP_001398956.1 | RNA binding protein fox-1 homolog 2 isoform 6 |
| NM_001412028.1 | NP_001398957.1 | RNA binding protein fox-1 homolog 2 isoform 32 |
| NM_001412029.1 | NP_001398958.1 | RNA binding protein fox-1 homolog 2 isoform 33 |
| NM_001412030.1 | NP_001398959.1 | RNA binding protein fox-1 homolog 2 isoform 34 |
| NM_001412031.1 | NP_001398960.1 | RNA binding protein fox-1 homolog 2 isoform 35 |
| NM_001412032.1 | NP_001398961.1 | RNA binding protein fox-1 homolog 2 isoform 36 |
| NM_053104.7 | NP_444334.3 | RNA binding protein fox-1 homolog 2 isoform 1 |
| NM_175387.4 | NP_780596.1 | RNA binding protein fox-1 homolog 2 isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables mRNA binding |
IDA
IDA: Inferred from direct assay
|
22357600 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
9185665 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within dendrite morphogenesis |
IMP
IMP: Inferred from mutant phenotype
|
22357600 | MGI |
| acts upstream of or within neuromuscular process controlling balance |
IGI
IGI: Inferred from genetic interaction
|
22357600 | MGI |
| acts upstream of or within radial glia guided migration of Purkinje cell |
IMP
IMP: Inferred from mutant phenotype
|
22357600 | MGI |
| acts upstream of or within regulation of alternative mRNA splicing, via spliceosome |
IGI
IGI: Inferred from genetic interaction
|
22357600 | MGI |
| acts upstream of or within regulation of alternative mRNA splicing, via spliceosome |
IMP
IMP: Inferred from mutant phenotype
|
22357600 | MGI |
| involved in regulation of alternative mRNA splicing, via spliceosome |
IMP
IMP: Inferred from mutant phenotype
|
17101796 | MGI |
| involved in regulation of definitive erythrocyte differentiation |
IDA
IDA: Inferred from direct assay
|
17715393 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
11401487 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
RNA binding protein fox-1 homolog 2 |
|
|
Related Agents
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Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS11725 | RBFOX2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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