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United States

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Cat. No.: HY-168184

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WJM280

WJM280 is an orally active antimalarial agent, with an EC₅₀ of 0.04 μM for P. falciparum 3D7 parasites.

For research use only. We do not sell to patients.

Formula: C₂₂H₂₅F₃N₂O
Molecular Weight:390.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

WJM280 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

WJM280 is an orally active antimalarial agent, with an EC₅₀ of 0.04 μM for P. falciparum 3D7 parasites^[1].

All Parasite Isoforms :

Chemical Information

Molecular Weight 390.44
Formula C₂₂H₂₅F₃N₂O
SMILES

O=C(NC1CC1)C2=CC=C(CN(CCC)CC3=CC=C(C(F)(F)F)C=C3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Awalt JK, et al. Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b. Eur J Med Chem. 2024 Oct 3;280:116921. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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WJM280

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

WJM280 Related Classifications

HY-168184 Related Classifications