ERβ agonist-2
ERβ agonist-2 (Page 72) is a selective ERβ agonist with an EC50 of 800 nM or lower. ERβ agonist-2 selectively inhibits T cell activation and/or proliferation, thereby reducing circulating T cell levels in subjects, without exerting significant effects on circulating neutrophil, monocyte or B cell levels. ERβ agonist-2 is applicable to studies of chronic heart failure after myocardial infarction, as well as graft-versus-host disease, multiple sclerosis and experimental autoimmune encephalomyelitis.
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- CAS 番号: 628321-25-5
- 分子式: C19H16N2O2
- 分子量:304.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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ERβ 800 or low nM (EC50) |
ERβ agonist-2 exhibits an EC50 of 800 nM or less at estrogen receptor β (ERβ)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 628321-25-5
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分子量 304.34
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分子式 C19H16N2O2
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SMILES
OC1=CC=C(C2=C(C3=C(C)ON=C3C)NC4=C2C=CC=C4)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
ERβ agonist-2 関連分類
HY-186074 関連分類
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