EZH2-IN-15
Based on 1 publication(s) in Google Scholar
EZH2-IN-15 is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.18%
- CAS 番号: 2098545-98-1
- 分子式: C32H44N4O4
- 分子量:548.72
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 EZH2-IN-15
MoreHistone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 2098545-98-1
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性状 Solid
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分子量 548.72
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分子式 C32H44N4O4
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Color Off-white to yellow
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SMILES
O=C1NC(C)=CC(C)=C1CNC(C2=C3C=C(CN4CCCCC4)OC3=CC(N(C5CCOCC5)CC)=C2CC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Death Dis
EZH2 inhibitor SHR2554 enhances the anti-tumor efficacy of HDAC inhibitor Chidamide through STAT1 in T-cell lymphoma. [Abstract]2025 Jul 14;16(1):522. PMID: 40659662
溶剤 & 溶解度
DMSO : 125 mg/mL (227.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8224 mL | 9.1121 mL | 18.2242 mL | 45.5606 mL |
| 5 mM | 0.3645 mL | 1.8224 mL | 3.6448 mL | 9.1121 mL | |
| 10 mM | 0.1822 mL | 0.9112 mL | 1.8224 mL | 4.5561 mL | |
| 15 mM | 0.1215 mL | 0.6075 mL | 1.2149 mL | 3.0374 mL | |
| 20 mM | 0.0911 mL | 0.4556 mL | 0.9112 mL | 2.2780 mL | |
| 25 mM | 0.0729 mL | 0.3645 mL | 0.7290 mL | 1.8224 mL | |
| 30 mM | 0.0607 mL | 0.3037 mL | 0.6075 mL | 1.5187 mL | |
| 40 mM | 0.0456 mL | 0.2278 mL | 0.4556 mL | 1.1390 mL | |
| 50 mM | 0.0364 mL | 0.1822 mL | 0.3645 mL | 0.9112 mL | |
| 60 mM | 0.0304 mL | 0.1519 mL | 0.3037 mL | 0.7593 mL | |
| 80 mM | 0.0228 mL | 0.1139 mL | 0.2278 mL | 0.5695 mL | |
| 100 mM | 0.0182 mL | 0.0911 mL | 0.1822 mL | 0.4556 mL |
EZH2-IN-15 関連分類
HY-153191 関連分類
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