Primpol - primase and polymerase (DNA-directed) Gene

Also Known as Ccdc111

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 408022

Summary

Enables DNA primase activity. Involved in mitochondrial DNA repair and mitochondrial DNA replication. Predicted to be located in replication fork. Predicted to be active in mitochondrial matrix and nucleus. Is expressed in several structures, including aorta; brain; endocrine gland; genitourinary system; and trachea. Human ortholog(s) of this gene implicated in myopia. Orthologous to human PRIMPOL (primase and DNA directed polymerase). [provided by Alliance of Genome Resources, Apr 2022]

Primpol Products (1)

mRNA Protein Name
NM_001001184.2 NP_001001184.1 DNA-directed primase/polymerase protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables DNA primase activity IDA
IDA: Inferred from direct assay
29073063 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in mitochondrial DNA repair IDA
IDA: Inferred from direct assay
29073063 MGI
involved in mitochondrial DNA replication IMP
IMP: Inferred from mutant phenotype
24207056 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed primase/polymerase protein

  • coiled-coil domain-containing protein 111

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11099 PRIMPOL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Primpol NCBI NCBI:201973