L-Alanine-15N
Based on 1 Customer Validation
L-Alanine-15N is the 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.88%
- CAS 番号: 25713-23-9
- 分子式: C3H715NO2
- 分子量:90.09
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 25713-23-9
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非標識Cas 56-41-7
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性状 Solid
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分子量 90.09
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分子式 C3H715NO2
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Color White to off-white
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SMILES
OC([C@@H]([15NH2])C)=O
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別名
L-2-Aminopropionic acid-15N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
H2O : 100 mg/mL (1110.00 mM; Need ultrasonic)
DMSO : 1 mg/mL (11.10 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 11.1000 mL | 55.5001 mL | 111.0001 mL | 277.5003 mL |
| 5 mM | 2.2200 mL | 11.1000 mL | 22.2000 mL | 55.5001 mL | |
| 10 mM | 1.1100 mL | 5.5500 mL | 11.1000 mL | 27.7500 mL | |
| H2O | 15 mM | 0.7400 mL | 3.7000 mL | 7.4000 mL | 18.5000 mL |
| 20 mM | 0.5550 mL | 2.7750 mL | 5.5500 mL | 13.8750 mL | |
| 25 mM | 0.4440 mL | 2.2200 mL | 4.4400 mL | 11.1000 mL | |
| 30 mM | 0.3700 mL | 1.8500 mL | 3.7000 mL | 9.2500 mL | |
| 40 mM | 0.2775 mL | 1.3875 mL | 2.7750 mL | 6.9375 mL | |
| 50 mM | 0.2220 mL | 1.1100 mL | 2.2200 mL | 5.5500 mL | |
| 60 mM | 0.1850 mL | 0.9250 mL | 1.8500 mL | 4.6250 mL | |
| 80 mM | 0.1388 mL | 0.6938 mL | 1.3875 mL | 3.4688 mL | |
| 100 mM | 0.1110 mL | 0.5550 mL | 1.1100 mL | 2.7750 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.